Thursday, November 29, 2012

Bukit Kiara football academy to help raise standard

Bukit Kiara Sports and Recreation Club?s football academy poised to help raise the football standard in Malaysia by developing young talents.

The academy which is located at Bandar Utama community football field has 17 boys undergoing football training under the tutelage of the head coach Saravanan.

Currently the academy is?utilizing?the basketball court as the makeshift training ground while waiting for the football field to be upgraded.

Saravanan, who is a former national footballer determined to develop the young talents and give them an avenue to shine.

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Source: http://cj.my/post/80334/bukit-kiara-football-academy-to-help-raise-standard/

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Egypt judges strike to protest president's decrees

CAIRO (AP) ? In an escalation of the tug-of-war between Egypt's president and the powerful judiciary, judges in the country's top courts went on strike Wednesday to protest Mohammed Morsi's seizure of near absolute powers, while Islamists rushed to complete a new constitution, the issue at the heart of the dispute.

The moves came a day after at least 200,000 protesters filled Cairo's central Tahrir Square to denounce the decrees Morsi issued last week, which place him above oversight of any kind, including by the courts.

Threatening to turn the dispute into violent street clashes, Morsi's Muslim Brotherhood and the more radical Islamist Salafi Al-Nour party, called for a counter-demonstration this weekend in Tahrir Square, where Morsi's opponents have been holding a sit-in for over a week.

Morsi says the decrees are necessary to protect the "revolution" that helped drive Hosni Mubarak from office last year as well as the nation's transition to democratic rule. The constitutional declaration also provides the 100-member panel drafting a new constitution with immunity from the courts.

In a sign the dispute may take a sharp turn, the Supreme Constitutional Court said in a statement that it will go ahead with plans to rule Sunday on whether to dissolve the assembly writing the new constitution, which is dominated by the Brotherhood and its Islamist allies.

"The court is determined to rise above its pain and continue its sacred mission until the end, wherever that takes us," Maher Sami, the high court's deputy chairman, said in a televised speech.

The expected decision on Sunday, regardless of which way it goes, would constitute a direct challenge to Morsi, who took office in June as Egypt's first freely elected president but has enraged pro-democracy activists who claim he is acting too much like the authoritarian leader he replaced.

Complicating matters, the constitutional panel was rushing to wrap up its work and some members said a final draft could be completed as early as Thursday. This would allow the president to call for a nationwide referendum on the document even before the court convenes Sunday, circumventing its decision.

In an unprecedented move, meanwhile, Egypt's highest appeal courts went on strike to protest the presidential decree. Judges with the high and lower courts of appeal said they would not return to work until Morsi rescinds his decrees, according to state TV. Many of the country's courts already had stopped functioning due to individual strikes.

The high court of appeal is led by Mohammed Mumtaz Metwali, who also chairs the Supreme Judiciary Council, which oversees the nation's court system. Members of the council met Morsi on Monday to discuss his decrees.

In a statement, judges of the high appeals court, known as the Court of Cassation, denounced Morsi's decrees as an "unprecedented" assault on the judiciary and its principles. It said the decision to halt work at all its circuits was justified by the "magnitude" of the crisis.

"This is the highest form of protest," said Nasser Amin, the head of the Arab Center for the Independence of the Judiciary and the Legal Profession.

Morsi and his allies in the Muslim Brotherhood have accused the judiciary of being dominated by Mubarak-era appointees who are trying to undermine the new leader, allegations the judges have rejected.

The constitutional court ruled in June to dissolve parliament's lower chamber, which is dominated by Islamists, on grounds that the law governing the elections didn't provide equal opportunities for candidates. There were warnings before the vote that such legal pitfalls might be forthcoming but the elections went ahead anyway.

The court denounced Morsi's claim that it was part of a "conspiracy" against him.

"The allegation that the (June) ruling was reached in complicity with others to bring down elected state institutions and consequently the state's collapse ... is incorrect and untrue," said Sami, the high court's deputy chairman.

In response to Tuesday's massive anti-Morsi protests, the Brotherhood and other Islamist parties announced plans to hold a rival rally on Saturday in Tahrir Square, dubbed "In support of legitimacy and Shariah (Islamic law)."

Previous rallies where Islamists and secular forces met in the square have turned violent.

The liberal opposition has said it will not enter a dialogue with the president about the country's latest political crisis until Morsi rescinds his decrees. Activists planned another massive rally on Friday.

Source: http://news.yahoo.com/egypt-judges-strike-protest-presidents-decrees-213322187.html

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Wednesday, November 28, 2012

Double duty: Immune system regulator found to protect brain from effects of stroke

ScienceDaily (Nov. 28, 2012) ? A small molecule known to regulate white blood cells has a surprising second role in protecting brain cells from the deleterious effects of stroke, Johns Hopkins researchers report. The molecule, microRNA-223, affects how cells respond to the temporary loss of blood supply brought on by stroke -- and thus the cells' likelihood of suffering permanent damage.

"We set out to find a small molecule with very specific effects in the brain, one that could be the target of a future stroke treatment," says Valina Dawson, Ph.D., a professor in the Johns Hopkins University School of Medicine's Institute for Cell Engineering. "What we found is this molecule involved in immune response, which also acts in complex ways on the brain. This opens up a suite of interesting questions about what microRNA-223 is doing and how, but it also presents a challenge to any therapeutic application." A report on the discovery is published in the Nov. 13 issue of the Proceedings of the National Academy of Sciences.

RNA is best known as a go-between that shuttles genetic information from DNA and then helps produce proteins based on that information. But, Dawson explains, a decade ago researchers unearthed a completely different class of RNA: small, nimble fragments that regulate protein production. In the case of microRNA, one member of this class, that control comes from the ability to bind to RNA messenger molecules carrying genetic information, and thus prevent them from delivering their messages. "Compared with most ways of shutting genes off, this one is very quick," Dawson notes.

Reasoning that this quick action, along with other properties, could make microRNAs a good target for therapy development, Dawson and her team searched for microRNAs that regulate brain cells' response to oxygen deprivation.

To do that, they looked for proteins that increased in number in cells subjected to stress, and then examined how production of these proteins was regulated. For many of them, microRNA-223 played a role, Dawson says.

In most cases, the proteins regulated by microRNA-223 turned out to be involved in detecting and responding to glutamate, a common chemical signal brain cells use to communicate with each other. A stroke or other injury can lead to a dangerous excess of glutamate in the brain, as can a range of diseases, including autism and Alzheimer's. Because microRNA-223 is involved in regulating so many different proteins, and because it affects glutamate receptors, which themselves are involved in many different processes, the molecule's reach turned out to be much broader than expected, says Maged M. Harraz, Ph.D., a research associate at Hopkins who led the study. "Before this experiment, we didn't appreciate that a single microRNA could regulate so many proteins," he explains.

This finding suggests that microRNA-223 is unlikely to become a therapeutic target in the near future unless researchers figure out how to avoid unwanted side effects, Dawson says.

Other authors on the paper are Stephen M. Eacker, Ph.D., Xueqing Wang, Ph.D., and Ted M. Dawson, M.D., Ph.D., from the Johns Hopkins University School of Medicine.

This work was supported by a grant from the National Institutes of Health (grant DA000266) and by a Maryland Stem Cell Research Fund fellowship.

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The above story is reprinted from materials provided by Johns Hopkins Medicine.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. W. Luo, R. Chang, J. Zhong, A. Pandey, G. L. Semenza. PNAS Plus: Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression. Proceedings of the National Academy of Sciences, 2012; DOI: 10.1073/pnas.1217394109

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/6wj-03lXm1Y/121128143549.htm

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Capital One survey: Texas consumer and business attitudes about ...

Attitudes about Texas? economic and employment climate improved in the third quarter, but business and personal finances remain fragile, according to a survey released today by Capital One Bank.

The quarterly Market Pulse survey found that 52 percent of Texas large businesses and 35 percent of small businesses reported that economic conditions are improving for their companies. Those results marked a 12-point drop for small businesses and a five-point decline for large businesses from second quarter.

?While we?ve seen a slight decline in business confidence and more businesses reporting drops in their financial performance, there is still an overall sense of strength and stability in the state?s economy,? said Kent Eastman, Texas State president for Capital One. ?Business plans for spending on investments remain on track, and we saw an increase in the number of businesses that are looking to hire right now and have plans to hire over the next six months. This is an encouraging sign.?

More than one-third of large and small companies plan to hire in the next six months, up from the second quarter.

That?s also reflected in Texas consumers, who are more optimistic about the job market than they?ve been in two years, the report found. Twenty percent said jobs are ?easy to find.?

Small businesses appear to be having a harder time than large businesses.

While the 36 percent of Texas small businesses planning to hire in the next six months is higher than the national average of 27 percent, the financial position of small firms is slightly worse than the national average and worse than larger companies.

Twenty-seven percent of small firms across Texas said their financial position was worse than last year, a 17-point increase from second quarter. That compares with 53 percent of large businesses that reported a better financial performance than last year. Small businesses said their biggest challenges are cash flow, price margins, customer payments and increased competition.

Texas consumer confidence in personal finances and business conditions rose from last year.

While 49 percent of Texas consumers say local business conditions are excellent or good, only 12 percent say that the local economy is excellent.

Just over one-third of consumers said that their personal financial position is better than a year ago, which dropped slightly from the second quarter. But 16 percent say their financial position is ?much better,? which is significantly higher than previous quarter.

Capital One surveyed by telephone 402 adults and 300 business owners or managers in Texas in September and early October.

Source: http://bizbeatblog.dallasnews.com/2012/11/capital-one-survey-texas-consumer-and-business-attitudes-about-the-economy-and-employment-improved-in-3q-but-personal-and-small-business-finances-remain-fragile.html/

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Verizon Sued By Porn Industry For Protecting Pirates

Verizon is being sued by a group of adult movie companies because it has refused to hand over personal details of alleged BitTorrent pirates. More »


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/B2RV-f9nIPo/verizon-sued-by-porn-industry-for-protecting-pirates

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Tuesday, November 27, 2012

Justin Bieber Overalls (PHOTO): Fashion Fail With Prime Minister

Yes, he is the biggest thing EVER to come out of Canada?eh? But the Justin Bieber overalls photo is hysterical ? and I can?t believe he would wear them to meet the Prime Minister. This owes him fashion fail of the utmost degree. Even scrappy, tattooed, herion-addict looking celebrities usually make an attempt at cleaning up if they are going to meet a dignitary. I think I?ve seen characters like Tommy Lee wearing suits ? even if they leave out the tie. So what if you are the biggest, most successful celebrity to come out of your country? Shouldn?t you at least throw on a button-up polo to meet the Prime Minister of said country? Sure. But my issue is not that he wore a ridiculous, striped, three-stooges outfit to accept a big award?.it?s that he wore it in the first place. One strap off, big, goofy hat on backwards and sideways, and a painfully ugly pair of shoes. Come on, Justin. You can do better. What do you think about the Justin Beiber overalls photo? Is it a total fail?

Source: http://feedproxy.google.com/~r/RightCelebrity/~3/JlD0CN6gtsc/

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The $400 million buyout hoax that fooled many

6 hrs.

The "pump and dump" lives, apparently.?

Shares of ICOA Wireless?soared earlier Monday on news that Internet behemoth Google had acquired the wireless hotspot company for $400 million. The problem? The buyout never happened.?

The CEO of ICOA told Reuters in an email Monday that it never had buyout talks with Google and that it has contacted authorities to look into what it called a hoax press release.

"Someone, I guess a stock promoter with a dubious interest, is disseminating wrong, false and misleading info in the PR circles,"?ICOA CEO and Chairman George Strouthopoulos told Reuters.

According to the Wall Street Journal's "All Things D" blog, the fake press release was disseminated on PRWeb, which is a free service operated by the PR firm Vocus. The Wall Street Journal called PRWeb to ask it about the press release, but has not heard back from anyone yet.

"We are investigating the source, so far it originated from Aruba," Strouthopoulos told Reuters. He did not ?elaborate.?

In the meantime, shares of ICOA retreated to .0001 cent in later afternoon trading?after rising to .0005 cent when the two paragraph press release got investors excited and fooled some news organizations and blogs.

That quick rise and fall could have spelled swift profits for some unscrupulous?investor or investors in the type of scheme that pumps up a stock price with false information. The investor(s) then dump the shares quickly before others in the market get wind of the misinformation. Hence the "pump and dump" moniker.

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Source: http://www.nbcnews.com/business/400-million-buyout-hoax-fooled-many-1C7208011

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